Kakashi & Itachi

Intro after the incident with the murder of the whole Uchiha Clan from Itachi and also at the time after the incident with betrayal of the Hidden Leaf Village from Kakashi both of them chosen themselves as a duo for the Akatsuki after Kakashi and Itachi actions their both had caused in both different ways to themselves Itachi and Kakashi connections grown together intense so they both end up as the first official Akatsuki Member duo