No, Lowe's is closed on Christmas Day. The stores are typically closed on major holidays like Christmas, Thanksgiving, and New Year's Day. It's important to plan ahead and stock up on any supplies or materials you might need before the holiday. Lowe's is open on other days, however, and you can always check their website for store hours and holiday closures. If you have a project or repair that needs to be completed on Christmas Day, there are other stores that may be open, so it's worth checking around.