No, unfortunately, Safeway is not open on Christmas Day. However, you can find a variety of stores and supermarkets that are open on Christmas Day, depending on where you live. You could try checking with local grocery stores or pharmacies to see if they have any locations that are open on Christmas Day. Additionally, there may be some convenience stores or gas stations that are open for a few hours on Christmas Day. It's always a good idea to check with your local businesses to see what their holiday hours are.