Bonnie Rockwaller is Kim Possible's Middleton High School classmate, fellow cheerleader, and her archrival since at least middle school.

Peko Pekoyama (辺古山 ペコ), is a student of Hope's Peak Academy's Class 77-B, and a participant of the Killing School Trip featured in Danganronpa 2: Goodbye Despair. Her title is the Ultimate Swordswoman (超高校級の「剣道家」 lit. Super High School Level Kendoka). She, along with Class 77-B, return in Danganronpa 3: The End of Hope's Peak High School to explore their school life leading up to The Tragedy.

She has the title Ultimate Writing Prodigy and she suffers from dissociative identity disorder. Her other personality comes out when she sneezes, or upon seeing blood (which also makes her faint prior). That other personality is known as Genocide Jack (also known as Genocide Jill or, in Japan, Genocider Syo, among those who aren't aware of her gender) who has the title Ultimate Murderous Fiend.

Princess Bubblegum is a Princess of Candy Kingdom

Marceline Abadeer (full title: Marceline the Vampire Queen) is one of the main characters in Adventure Time and the main protagonist of the miniseries Stakes.

Kimberly Ann "Kim" Possible is a high school student and freelance hero/vigilante. She is unusual not to mention the fact that she not only lacks a secret identity, but also remains on good terms with various law enforcement, government, and military agencies. For the most part, her schoolmates are aware of her work but don't do anything about it unless it somehow affects them directly. At school, Kim is the head of her cheerleading squad and a straight-A student, rather than as a misunderstood outsider/underdog as typical of the genre.

Kimberly Ann "Kim" Possible is a high school student and freelance hero/vigilante. She is unusual not to mention the fact that she not only lacks a secret identity, but also remains on good terms with various law enforcement, government, and military agencies. For the most part, her schoolmates are aware of her work but don't do anything about it unless it somehow affects them directly. At school, Kim is the head of her cheerleading squad and a straight-A student, rather than as a misunderstood outsider/underdog as typical of the genre.

Shego is a villainess who operates as a criminal mercenary, working for Dr. Drakken as his chief enforcer and henchwoman/sidekick. Since her main duty to Drakken entails stealing things on his request and protecting him from harm, she frequently engages Team Possible in battle, and although she is under contract with the scientist, Shego has occasionally (temporarily) worked with other villains as well, including Motor Ed and Señor Senior, Junior.

Lady Arlecchino (originally Peruere Snezhevna), also known as The Knave, the Fourth of the Eleven Fatui Harbingers, Father, and the Cinder of Two Worlds' Flames