Colin is the main protagonist in the game Changed, a scrawny man with amnesia trying to escape a lab filled with latex creatures. He relies on his wits, speed, and Puro's help to survive. Colin's main goal is to escape to the outside world, facing constant danger and transformations by the latex beasts. He carries the deadly Pale Virus unknowingly, which is slowly killing him. Throughout the game, Colin faces various transformations and tragic fates, including becoming a latex or non-latex wolf, while retaining his blue eyes.

Tiger Shark is a boss enemy in Changed, found in the Aquatic Area. It summons sharks and can be challenging due to spawning entities causing lag. In the Special Edition, it may wave goodbye with high friendship levels. It can be temporarily stuck in garbage but not recommended in its final phase. It can be skipped by slipping past the blocking shark. DragonSnow once sold Tiger Shark dolls. To outlast its attacks, avoid changing direction until the second visual cue. Gas canisters can be used to trick sharks but can despawn if bumped into.

The Ming Cat is a fast and deadly adversary encountered in the game, known for its speed and lethal intentions towards its prey. It can be distracted with decoys and slowed down by stepping on its latex residue patches. It is last seen transformed into a humanoid-cat and relaxing happily. In Chinese, the Ming Cat is referred to as 冥猫.

The Moth is a small variegated-latex moth in the Vents kept by the Stiger. It appears as a small tan latex moth with multicolored wings. After transfurring the protagonist, it becomes an anthropomorphic moth with white markings. It is slow and not a threat, but the Stiger may use it as bait for traps. The Stiger may attempt to eat the protagonist post-transfur due to the predator-prey relationship between spiders and moths.The Moth is a small variegated-latex moth in the Vents, kept by the Stiger. It appears as a small tan latex moth with multicolored wings. After transfurring the protagonist, it becomes an anthropomorphic moth with white markings. It is slow and not a significant threat, except potentially falling for traps set by the Stiger. The Stiger seems to web up the Human post-transfur, possibly with the intent of eating them due to the predator-prey relationship between spiders and moths.

The Stiger is a mischievous creature resembling a hybrid of a tiger and a spider, with six arms, bright magenta eyes, and a spider abdomen. It plays pranks on the protagonist, such as stealing items and trapping them with latex webs. The Stiger is described as a prankster with high mental capacity and enjoys setting traps and laughing at those who fall for them.

The Purple Fox is a friendly purple variegated-latex fox found in the vents. It has a special relationship with No. 25 and can fuse and separate from it, kissing when they reunite. It is docile with other foxes but may 'transfur' Colin if he collides with it. The Purple Fox blushes and smiles after kissing Colin.

Puro is a dark latex creature in the game Changed who initially plans to assimilate humans but later befriends the protagonist. He displays characteristics of both genders but identifies as male. Puro is unique as he resists his instinct to swallow up humans and becomes a protective older brother figure to the protagonist. The word "puro" translates to "Pure/To Purify" in many languages and could be a corruption of the Japanese word for the color black.

Circle is a fox-like variegated-latex creature that creeps along ceilings. It has white fur, red stripes, and light pink pawpads. Circle is slow-moving and hangs from the ceiling in groups, only coming down if a human gets close enough. Raised by Puro, Circle multiplied unchecked in the library and Dr. K's laboratory.

The Squid Pups are squid-dog hybrids in the game's aquatic area. They have tentacles, white fur, and four arms. They can assimilate humans and swim faster than sharks. In a boss battle, they can be found in a boat or hiding in a box. They can also interact with sharks, leading to playful fights.

Poe is a sophisticated crow in the Ruby Gloom franchise, known for his talkative and pampered nature. He is a caring friend and loves his brothers Edgar and Allan. Poe appears in 36 out of 40 episodes and has a signature dance move of hopping between claws and swatting.

The Five-Tailed-Fox, as it's name suggests, is a fox-like variegated-latex beast that can be found in the Cage Room, a hidden room in the Greenhouse area of the Special Edition.The Five-Tailed Fox is mainly black, except for pink striped patterns on it's tail and eyebrows. After assimilating Colin, it gains a more anthropomorphic appearance, manifesting as a kitsune-like fox with five tails, and it’s peculiar black and pink markings are much more fantastical now that the creature has been able to fuse together. It can take over Colin easily with a snap of its fingers.The two foxes are adorable but dangerous, just like all other latex creatures, immediately assimilating Colin, and asserting dominance over him by snapping it’s fingers.The Five-Tailed Fox is a black fox-like creature with pink striped patterns on its tail and eyebrows. After assimilating Colin, it transforms into a kitsune-like fox with five tails and gains the ability to take over Colin with a snap of its fingers.

Skull Boy from Ruby Gloom is a versatile character who enjoys activities like painting, filmmaking, cooking, exploring, and investigating. He is curious about his ancestry and often imagines himself in various roles to find his identity. He is oblivious to Ruby's crush on him, and they share a close bond in Gloom Manor. Skull Boy appears in most episodes of the series and has a signature dance move of freeze frames. In the original merchandise, he was depicted as a human wearing a skull mask out of shyness. He is speculated to be around 11 or 12 years old.

Boo-Boo White is a mischievous ghost in Ruby Gloom who enjoys pranking more than scaring. He becomes a full ghost after accidentally scaring Misery. Despite his job as a scarer, he is more of a prankster and enjoys tormenting Scaredy Bat. His voice actress is Barbara Mamabolo.

The Sludge Villain is a D-rank villain who tries to possess Izuku and Katsuki, shows cowardice in the Final War, escapes custody, and joins the Paranormal Liberation Front. He assimilates Hitoshi Shinso, but is frozen by Hitoshi's Brainwashing. Hitoshi then brainwashes Gigantomachia to attack the villains. The Sludge Villain and other defeated villains are detained and arrested. His Quirk transforms his body into a mud-like substance, granting immunity to physical attacks, ability to possess others, but is weak to acid and wind pressure. Voiced by Jeremy Inman, who also voiced Kenji Hikiishi.

Bee☆Pop is a villain in My Hero Academia: Vigilantes who controls a human host and a swarm of worker bees. She can create Bomb Bees that explode when ordered, causing damage. Bee☆Pop also possesses the Quirk Leap, allowing her to jump high but needing a solid surface to leap off. Trigger enhances her abilities, and damage to her bees affects her.

A hitchhiker torments a woman who accidentally killed him, repeatedly reappearing and haunting her until she meets a tragic end.

In the film "The Crate" from Creepshow, a janitor discovers a man-eating Arctic monster named Fluffy in a mysterious crate at a university. Fluffy escapes, wreaking havoc and devouring people. Eventually, Fluffy is contained again and dumped into a quarry lake, seemingly defeated. However, Fluffy survives and breaks free to continue its rampage. Fluffy never attempts to leave its crate and only attacks in self-defense, resembling the cryptid Yeti. The origins of Fluffy and its motives remain a mystery.