Ichiru Kiryu (錐生 壱縷, Kiryū Ichiru) was the younger twin brother of Zero Kiryu. When they were children, they were both taught by Toga Yagari to become vampire hunters. Ichiru, however, did not seem to have the same talent as Zero's natural ability, as he was often ill.

Takuma Ichijo (一条 拓麻, Ichijō Takuma) is a member of the Ichijo Family and the Vice-President of the Night Class at Cross Academy. He is an Aristocrat Vampire and is good friends with Kaname Kuran, whom he is close to and respects. He also possesses the ability to disintegrate matter.

Akatsuki Kain (架院 暁, Kain Akatsuki) is Hanabusa Aido's cousin and one of Kaname's "right hands." He is nicknamed "Wild" by several girls of the Day Class due to wearing his shirt unbuttoned. His nickname contradicts his mellow personality.

Senri Shiki (支葵 千里, Shiki Senri) is an aristocrat, a model, and one of the youngest Night Class students. Later on, it is revealed that he is the illegitimate son of Rido Kuran.

Hanabusa Aido (藍堂 英, Aidō Hanabusa), nicknamed "Idol" by the Day Class girls, is a member of and the heir of the Aido Family, protector and tutor of Yuki Kuran and the cousin of Akatsuki Kain and Ruka Souen. Hanabusa is an Aristocrat Vampire who possesses the ability to freeze matter.

Zero Kiryu (錐生 零, Kiryū Zero) is both an ex-human vampire and a vampire hunter. Zero is the older twin brother of Ichiru Kiryu, Yuki Kuran's partner, and the biological father of Ren Kiryu.

Kaname Kuran (玖蘭 枢 Kuran Kaname) was a Pureblood vampire and Head of the Kuran family, one of the seven remaining Pureblood families who was also one of the progenitors of the Vampires and the first Kuran, giving him an estimated age of 11,000 years old. Kaname is the fiancé of Yuki Cross and the biological father of Ai Kuran.

Seiren (星煉, Seiren), born Hoshino (星乃), is a student of the Night Class at Cross Academy and the unofficial bodyguard/faithful follower of Kaname Kuran.

Sayori "Yori" Aido (藍堂 沙頼 Aidō Sayori), née Wakaba (若葉), was Yuki Kuran's dorm-mate and best friend since junior high at Cross Academy. She is a Human and joins the Aido Family through marriage.

Maria Kurenai (紅 まり亜, Kurenai Maria) is a sickly girl who was the new Night Class student at Cross Academy and a very distant relative of the late Shizuka Hio.

Ruka Souen (早園 瑠佳, Sōuen Ruka) is a female student of the Night Class and one of the most faithful, protective and loyal followers of Kaname Kuran.

Rima Toya (遠矢 莉磨, Tōya Rima) is one of the youngest Night Class students and the roommate of Ruka Souen. She has a close friendship with and eventually marries Senri Shiki, whom she works with as a model.

Yuki Cross (黒主 優姫, Kurosu Yūki) is the main protagonist of the Vampire Knight series. She is a former student and Guardian of Cross Academy. She is later revealed to be the Pureblood daughter of the Kuran family later awakened as a Vampire by Kaname Kuran, subsequently becoming Yuki Kuran (玖蘭 優姫, Kuran Yūki). Following this, she leaves Cross Academy with Kaname as his fiancé, but later returns to the Night Class to help the students coexist as originally planned.

Miyuki is an Highschool student who lives with her step dad. She is quiet, gentle and emotionally reserved.

Konami is one of the main female characters from the anime series "HHH Triple Ecchi". She is kindhearted and loving

She may look perfect from the outside, but she has a bad habit of lust in school. This is where her true-self was discovered by a guy who had been secretly in love with her. What was shocking is - instead of feeling threaten by the same person, she wants to love him more

A university student living in an apartment near the Shirakawa family. Although he has no blood connection with the Shirakawa sisters, they grew up like brother and sister since he was a child, so he loves them like a real sister.

The older of the Shirakawa sisters. A highly beauty-conscious person, she's the type who saves up her allowance to buy bath salts for her skin, and is devoted to self-improvement. She tends to have a reflexively cold attitude towards Kazushi, but at heart she worries that she can't be upfront about her feelings with him.

Vali Lucifer is the leader of the Vali Team that was previously affiliated with the Khaos Brigade, now a part of Team DxD. He is the remaining descendant of the original Lucifer and the wielder of the Longinus; Divine Dividing, being the possessor of the Vanishing Dragon, Albion. As such, he is the direct rival of Issei Hyoudou and Ddraig.